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hi i tried running my php mailer function from local host and everything s working fine, but when i host it to server its giving me an error

"2014-07-17 13:53:48 SMTP ERROR: Failed to connect to server: No connection could be made because the target machine actively refused it. (10061) SMTP connect() failed. Message could not be sent.Mailer Error: SMTP connect() failed."

im using class.phpmailer new version and setting r

$mail = new PHPMailer;

$mail->IsSMTP();
$mail->Host = 'mail.<domainname>.in';
$mail->SMTPAuth = true;
$mail->SMTPDebug = 1;
$mail->Username = 'info@<domainname>.in';
$mail->Password = 'mypassowrd';
$mail->setFrom('info@<domainname>.in', 'First Last');